Yike N. Zhang

@ Engineering Department in St. Mary's University

Hello! I'm Dr. Yike Zhang, a computer scientist with a research focus on LLM, Computer Vision, 6D Pose Estimation, and surgical navigation systems. I recently completed my Ph.D. in Computer Science at Vanderbilt University, where I developed a deep-learning-based navigation system for image-guided cochlear implant surgery. My work bridges machine learning and medical imaging processing, aiming to improve surgical accuracy, safety, and future clinical translation with real-time image analysis and intraoperative navigation tools.

Beyond research/teaching, I’m passionate about mentoring students, encouraging interdisciplinary collaboration, and creating open-source tools that support the wider medical imaging processing community. I enjoy building robust, intuitive systems that are both theoretically grounded and practically useful in high-stakes environments like the OR.

Outside of work, I enjoy hiking and traveling, and I love exploring new places and discovering local food scenes. Baking is one of my favorite creative activity β€” whether it’s sourdough, cakes, or cookies, I enjoy sharing what I make with friends. I also appreciate fun conversations about science, life, and technology.

πŸ“ Currently based in San Antonio, TX
πŸ“« yzhang5@stmarytx.edu


Teaching


Latest Posts

June 10, 2025 Completed my Ph.D. in Computer Science
May 2, 2025 Dissertation Completed πŸŽ‰
Feb 15, 2025 Our paper "SSDD-GAN: Single-Step Denoising Diffusion GAN for Cochlear Implant Surgical Scene Completion" got accepted to MIDL 2025

Selected Publications

2025

  1. SSDD-GAN: Single-Step Denoising Diffusion GAN for Cochlear Implant Surgical Scene Completion
    Yike Zhang, Eduardo Davalos, and Jack Noble
    Accepted to Medical Imaging with Deep Learning 2025

2025

  1. Self-supervised Mamba-based Mastoidectomy Shape Prediction for Cochlear Implant Surgery
    Yike Zhang, Eduardo Davalos, Dingjie Su, Ange Lou, and Jack Noble
    Medical Imaging 2025: Image Processing

2025

  1. Zero-shot Surgical Tool Segmentation in Monocular Video using Segment Anything Model 2
    Ange Lou*, Yamin, Li*, Yike Zhang*, Robert F. Labadie, and Jack Noble
    Medical Imaging 2025: Image Processing

2025

  1. Surgical Depth Anything: Depth Estimation for Surgical Scenes using Foundation Models
    Ange Lou, Yamin, Li, Yike Zhang, and Jack Noble
    Medical Imaging 2025: Image-Guided Procedures, Robotic Interventions, and Modeling

2024

  1. A First Step in Using Machine Learning Methods to Enhance Interaction Analysis for Embodied Learning Environments
    Joyce Fonteles, Eduardo Davalos, TS Ashwin, Yike Zhang, Mengxi Zhou, Efrat Ayalon, Alicia Lane, Selena Steinberg, Gabriella Anton, Joshua Danish, Noel Enyedy, and Gautam Biswas
    International Conference on Artificial Intelligence in Education

2024

  1. Monocular Microscope to CT Registration Using Pose Estimation of the Incus for Augmented Reality Cochlear Implant Surgery
    Yike Zhang, Eduardo Davalos, Dingjie Su, Ange Lou, and Jack Noble
    Medical Imaging 2024: Image-Guided Procedures, Robotic Interventions, and Modeling

2023

  1. Self-supervised Registration and Segmentation on Ossicles with A Single Ground Truth Label
    Yike Zhang and Jack Noble
    Medical Imaging 2023: Image-Guided Procedures, Robotic Interventions, and Modeling

2023

  1. Chimerapy: A Scientific Distributed Streaming Framework for Real-time Multimodal Data Retrieval and Processing
    Eduardo Davalos, Umesh Timalsina, Yike Zhang, Jiayi Wu, Joyce Horn Fonteles, and Gautam Biswas
    IEEE International Conference on Big Data (BigData)

2022

  1. Vector-based Efficient Data Hiding in Encrypted Images via Multi-MSB Replacement
    Yike Zhang and Wenbin Luo
    IEEE Transactions on Circuits and Systems for Video Technology